Managing global applications, especially those necessitating a validated approach, requires more than just technical expertise - it demands strong governance, cross-team alignment, and continuous refinement. This session examines Boehringer Ingelheim end-to-end, integrated framework that bridges business and IT, streamlines operations, and ensures compliance across cloud and on-prem systems. Learn how they addressed process harmonization across regions, enabled change traceability, streamlined operations through automation, and more. Although designed for a validated environment, Boehringer's integrated framework serves as a blueprint for managing complexity at scale across hybrid SAP landscapes, regardless of industry.